Research

The COM-IN Collaboratory works at the nexus of systems engineering, medicine, and healthcare informatics to develop, study, and evaluate digital health tools and technologies. The following are some of our current research projects: 

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Integrative Clinical Decision Support for Critical Care Medicine

Intensive Care Units (ICUs) are data-intensive environments, designed to provide additional support and closer/continuous monitoring for critically-ill patients. Currently, there is limited support for intensivists to effectively retrieve and use meaningful information for management and prognosis of ICU patients. This project involves developing and implementing novel ways of providing clinical decision support (CDS) in the ICUs as well as evaluating and validating early prototypes of CDS modules.

Patient State Modeling for Traumatic Brain Injury Stratification

Traumatic Brain Injury (TBI) is the leading cause of death and disability in children and adults of age less than 44. A significant challenge in both TBI care and research is the ability to identify cohorts from a highly heterogeneous trauma population. We are actively pursuing computational approaches to identify and characterize pathophysiologic states following TBI as a means of stratification for clinical trials and/or prognosis. 

 Systems Engineering to Improve Neurotrauma Care

Trauma patients, particularly TBI patients, go through a complex care delivery process from injury through longer-term care and recovery. We are particularly interested in capturing the continuum of trauma care and addressing important gaps and challenges through systems engineering approaches. This includes studying standardized TBI assessments and outcomes, interoperability between systems, and detailed data and information flow across the care delivery system.